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Index > Protein center > TLR6(Gene name) > Bovine
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  • TLR6 (Gene name),
  • Toll-like receptor 6 (Protein name ),  TLR6_BOVIN from NCBI database.
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  • General Annotation
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  • Gene name:
    TLR6;
    Protein name:
    Toll-like receptor 6;
    Alternative:

    CD:
    CD286;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Binds TLR2 via their respective extracellular domains. Binds MYD88 via their respective TIR domains.
    Function:
    Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Cytoplasmic vesicle phagosome membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    793
    Sequence:
    50:
    MIKDKESPIR | SCHFVYIVAL | VFGTIIQFSD | ESEFVVDMSK | TSLIHVPKDL | 
    100:
    PPKTKVLDLS | QNNISELHLS | DISFLSGLRV | LRLSHNRIQG | LDISIFKFNH | 
    150:
    DLEYLDLSHN | QLQKISCHPI | TTTLKHLDLS | FNDFDALPIC | KEFGNLTQLN | 
    200:
    FLGLSATKLQ | QLDLLPIAHL | HLSCILLDLE | DYMKENKKES | LQILNTKKLH | 
    250:
    LVFHPNSFFS | VQVDISANSL | GCLQLTNIKL | NDYNCQVLLK | FLSGLTGGPT | 
    300:
    LLNFTLNHVE | TTWKCLVKVF | QFLWPKPIEY | LNIYNLTIVE | SIDEEVFTYY | 
    350:
    KTTLKALKIE | HITNKVFIFS | QTALYTVFSE | MNILMLTISD | TRFIHMLCPQ | 
    400:
    EPSTFKFLNF | TQNSFTDSVF | QNCDTLARLE | TLILQKNELK | DLFKTSLMTK | 
    450:
    DMLSLETLDV | SWNSLEYDRS | NGNCSWVGSI | VVLNLSSNAL | TDSVFRCLPP | 
    500:
    RIKVLDLHNN | RIRSIPKDVT | GLETLQELNL | ASNSLAHLPG | CGIFSSLSIL | 
    550:
    IIEHNSISNP | SADFFQSCQK | IRSLKAGNNP | FQCSCELRDF | IQSVGQVSSD | 
    600:
    VVEGWPESYK | CDYPESYKGT | PLKDFQVSEL | SCNTALLIIT | IVVPGLVLAV | 
    650:
    AVTVLCIYLD | LPWYLRMVCQ | WTQTRRRARN | VPLEELQRTL | QFHAFISYSE | 
    700:
    HDSAWVKNEL | IPNLEKEDIR | ICLHERNFVA | GKSIVENIIN | CIEKSYKSIF | 
    750:
    VLSPNFVQSE | WCHYELYFAH | HNLFHEGSDN | LILILLDPIP | QYSIPSSYHK | 
    793:
    LRALMAQRTY | LEWPKEKSKH | GLFWANLRAS | INIKLMEKAA | EIH
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    SMR:
    Pfam:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Toll-like receptor 6
    Cat.:
    E0683m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Bovine Toll-like receptor 6
    Cat.:
    E0683h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Toll-like receptor 6
    Cat.:
    E0683b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Toll-like receptor 6
    Cat.:
    U0683m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Toll-like receptor 6
    Cat.:
    U0683h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Toll-like receptor 6
    Cat.:
    U0683b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Toll-like receptor 6
    Polyclonal Antibody for Bovine Toll-like receptor 6
    Cat.:
    P0683Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Toll-like receptor 6
    Cat.:
    P0683Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Toll-like receptor 6
    Monoclonal Antibody for Bovine Toll-like receptor 6
    Monoclonal Antibody for Bovine Toll-like receptor 6
    Protein for Bovine Toll-like receptor 6
    Protein for Bovine Toll-like receptor 6
    Protein for Bovine Toll-like receptor 6

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    References
    1. 1.
      "Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells-potential role in pathogen discrimination?"
      Werling D. , Piercy J. , Coffey T.J.
      Vet. Immunol. Immunopathol.112:2-11(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Analysis of sequence variability and protein domain architectures for bovine peptidoglycan recognition protein 1 and Toll-like receptors 2 and 6."
      Seabury C.M. , Womack J.E.
      Genomics92:235-245(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASN-214
      strain: Angus.
      strain: Charolais.
      strain: Holstein.
      strain: Limousin.
    3. 3.
      "Structure and tissue-specific expression the bovine TLR6-encoding gene."
      Yang W. , Weikard R. , Zerbe H. , Seyfert H.M.
      Submitted (2004-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      tissue: Mammary gland.
    4. 4.
      "Genomic organization and transcript profiling of the bovine toll-like receptor gene cluster TLR6-TLR1-TLR10."
      Opsal M.A. , Vage D.I. , Hayes B. , Berget I. , Lien S.
      Gene384:45-50(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 165-422;TISSUE SPECIFICITY;VARIANT ASN-214
      tissue: Semen.
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